Cargando…

Design of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepatitis C virus

Recently, peptide drugs have evolved into mainstream therapeutics, representing a significant portion of the pharmaceutical market. However, their bioavailability remains to be improved compared with that of chemical drugs. Here, we screened and identified a new peptide, Ctry2459, from a scorpion ve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Wei, Zhang, Runhong, Di, Zhiyong, He, Yawen, Zhao, Zhenhuan, Hu, Jun, Wu, Yingliang, Li, Wenxin, Cao, Zhijian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124613/ https://www.ncbi.nlm.nih.gov/pubmed/23415044 http://dx.doi.org/10.1016/j.biomaterials.2013.01.075

Ejemplares similares

Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1
por: Zeng, Zhengyang, et al.
Publicado: (2018)

Inhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1
por: Hong, Wei, et al.
Publicado: (2014)

The scorpions of Yunnan (China): updated identification key, new record and redescriptions of Euscorpiops kubani and E. shidian (Arachnida, Scorpiones)
por: Di, Zhiyong, et al.
Publicado: (2011)

Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components
por: Ruiming, Zhao, et al.
Publicado: (2010)

Different Biological Activities of Histidine-Rich Peptides Are Favored by Variations in Their Design
por: Lointier, Morane, et al.
Publicado: (2021)

Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus
por: Cheng, Yuting, et al.
Publicado: (2020)

Overview of Scorpion Species from China and Their Toxins
por: Cao, Zhijian, et al.
Publicado: (2014)

Notes on the scorpions (Arachnida, Scorpiones) from Xizang with the redescription of Scorpiops jendeki Kovařík, 2000 (Scorpiones, Euscorpiidae) from Yunnan (China)
por: Di, Zhiyong, et al.
Publicado: (2013)

Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses
por: Li, Qiaoli, et al.
Publicado: (2011)

Interaction of a Histidine-Rich Antimicrobial Saliva Peptide with Model Cell Membranes: The Role of Histidines
por: Skog, Amanda E., et al.
Publicado: (2023)

Biological activities of histidine-rich peptides; merging biotechnology and nanomedicine
por: Ferrer-Miralles, Neus, et al.
Publicado: (2011)

Bioactivity and Bactericidal Mechanism of Histidine-Rich β-Hairpin Peptide Against Gram-Negative Bacteria
por: Dong, Na, et al.
Publicado: (2019)

Correction: Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom
por: Song, Yu, et al.
Publicado: (2022)

Unique insertion/deletion polymorphisms within histidine-rich region of histidine-rich glycoprotein in Thoroughbred horses
por: Muko, Ryo, et al.
Publicado: (2023)

Antibacterial Activity and Mechanism of a Scorpion Venom Peptide Derivative In Vitro and In Vivo
por: Cao, Luyang, et al.
Publicado: (2012)

Hp1404, a New Antimicrobial Peptide from the Scorpion Heterometrus petersii
por: Li, Zhongjie, et al.
Publicado: (2014)

Genetic variations in histidine-rich protein 2 and histidine-rich protein 3 of Myanmar Plasmodium falciparum isolates
por: Lê, Hương Giang, et al.
Publicado: (2020)

Modified branched peptides with a histidine-rich tail enhance in vitro gene transfection
por: Leng, Qixin, et al.
Publicado: (2005)

Transcriptome analysis of the venom gland of the scorpion Scorpiops jendeki: implication for the evolution of the scorpion venom arsenal
por: Ma, Yibao, et al.
Publicado: (2009)

Metal complexation by histidine-rich peptides confers protective roles against cadmium stress in Escherichia coli as revealed by proteomics analysis
por: Isarankura-Na-Ayudhya, Patcharee, et al.
Publicado: (2018)

Histidine-rich glycoprotein: antithrombosis without bleeding
por: Schmaier, Alvin H.
Publicado: (2023)

Histidine-rich glycoprotein attenuates catheter thrombosis
por: Malik, Rida A., et al.
Publicado: (2023)

A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA
por: Zeng, Zhengyang, et al.
Publicado: (2016)

The Role of Copper (II) on Kininogen Binding to Tropomyosin in the Presence of a Histidine–Proline-Rich Peptide
por: Santoro, Anna Maria, et al.
Publicado: (2020)

Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel
por: Chen, Zongyun, et al.
Publicado: (2015)

A Scorpion Defensin BmKDfsin4 Inhibits Hepatitis B Virus Replication in Vitro
por: Zeng, Zhengyang, et al.
Publicado: (2016)

Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions
por: Cragnell, Carolina, et al.
Publicado: (2019)

Histidine Ligated Iron‐Sulfur Peptides
por: Valer, Luca, et al.
Publicado: (2022)

Selective Intracellular Delivery of Thiolated Cargo to Tumor and Neovasculature Cells Using Histidine-Rich Peptides as Vectors
por: Eksteen, J. Johannes, et al.
Publicado: (2020)

Design, Synthesis, and Evaluation of Homochiral Peptides Containing Arginine and Histidine as Molecular Transporters
por: El-Sayed, Naglaa Salem, et al.
Publicado: (2018)

Histidine-rich glycoprotein as an excellent biomarker for sepsis and beyond
por: Nishibori, Masahiro, et al.
Publicado: (2018)

Histidine-rich glycoprotein as a prognostic biomarker for sepsis
por: Kuroda, Kosuke, et al.
Publicado: (2021)

Deletion of Plasmodium falciparum Histidine-Rich Protein 2 (pfhrp2) and Histidine-Rich Protein 3 (pfhrp3) Genes in Colombian Parasites
por: Murillo Solano, Claribel, et al.
Publicado: (2015)

Therapeutic Potential of a Scorpion Venom-Derived Antimicrobial Peptide and Its Homologs Against Antibiotic-Resistant Gram-Positive Bacteria
por: Liu, Gaomin, et al.
Publicado: (2018)

Diverse Structural Features of Potassium Channels Characterized by Scorpion Toxins as Molecular Probes
por: Zhao, Yonghui, et al.
Publicado: (2019)

C-Terminal Amination of a Cationic Anti-Inflammatory Peptide Improves Bioavailability and Inhibitory Activity Against LPS-Induced Inflammation
por: Zhang, Lulu, et al.
Publicado: (2021)

Antithrombin protects against Plasmodium falciparum histidine-rich protein II-mediated inflammation and coagulation
por: Biswas, Indranil, et al.
Publicado: (2022)

SdPI, The First Functionally Characterized Kunitz-Type Trypsin Inhibitor from Scorpion Venom
por: Zhao, Ruiming, et al.
Publicado: (2011)

Histidine-Rich Glycoprotein Protects from Systemic Candida Infection
por: Rydengård, Victoria, et al.
Publicado: (2008)

Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes
por: Tugues, Sònia, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_e7i7846ulnvdlp9grvre4nco3a