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Teenager with a Primary Renal Lymphoma: A Case Report

We report a case of an 18-year-old male patient who was diagnosed with primary renal lymphoma (PRL) through biopsy findings and imaging studies. The patient presented with clinical manifestations of distal renal tubular acidosis including polyuria, polydipsia, lower limb weakness, involuntary weight...

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Autores principales: Arriola-Montenegro, Liliana, Palacios-Revilla, Cecilia D, Cateriano-Alberdi, Maria Paula, Valdivia-Vega, Renzo P, Arriola-Montenegro, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124830/
https://www.ncbi.nlm.nih.gov/pubmed/32257721
http://dx.doi.org/10.7759/cureus.7181
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author Arriola-Montenegro, Liliana
Palacios-Revilla, Cecilia D
Cateriano-Alberdi, Maria Paula
Valdivia-Vega, Renzo P
Arriola-Montenegro, Jose
author_facet Arriola-Montenegro, Liliana
Palacios-Revilla, Cecilia D
Cateriano-Alberdi, Maria Paula
Valdivia-Vega, Renzo P
Arriola-Montenegro, Jose
author_sort Arriola-Montenegro, Liliana
collection PubMed
description We report a case of an 18-year-old male patient who was diagnosed with primary renal lymphoma (PRL) through biopsy findings and imaging studies. The patient presented with clinical manifestations of distal renal tubular acidosis including polyuria, polydipsia, lower limb weakness, involuntary weight loss, asthenia and dyspnea. No personal background or relevant medical history was reported. A kidney biopsy showed high grade immature B-cell lymphoproliferative process (Non-Hodgkin’s Lymphoma) with a Ki67 value greater than 90%. Complementary studies excluded primary lymphoid migration sites, which confirmed the diagnosis of PRL. The oncology unit initiated treatment with a combination of medications due to lack of protocols for the specific treatment. Besides the fact that this condition is rare, it also shows a unique symptoms presentation and non-typical findings in imaging methods. Also, it is important to underline the fact that the treatment is not yet specified for such type of cancer and different combinations are needed to control the disease.
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spelling pubmed-71248302020-04-06 Teenager with a Primary Renal Lymphoma: A Case Report Arriola-Montenegro, Liliana Palacios-Revilla, Cecilia D Cateriano-Alberdi, Maria Paula Valdivia-Vega, Renzo P Arriola-Montenegro, Jose Cureus Pediatrics We report a case of an 18-year-old male patient who was diagnosed with primary renal lymphoma (PRL) through biopsy findings and imaging studies. The patient presented with clinical manifestations of distal renal tubular acidosis including polyuria, polydipsia, lower limb weakness, involuntary weight loss, asthenia and dyspnea. No personal background or relevant medical history was reported. A kidney biopsy showed high grade immature B-cell lymphoproliferative process (Non-Hodgkin’s Lymphoma) with a Ki67 value greater than 90%. Complementary studies excluded primary lymphoid migration sites, which confirmed the diagnosis of PRL. The oncology unit initiated treatment with a combination of medications due to lack of protocols for the specific treatment. Besides the fact that this condition is rare, it also shows a unique symptoms presentation and non-typical findings in imaging methods. Also, it is important to underline the fact that the treatment is not yet specified for such type of cancer and different combinations are needed to control the disease. Cureus 2020-03-04 /pmc/articles/PMC7124830/ /pubmed/32257721 http://dx.doi.org/10.7759/cureus.7181 Text en Copyright © 2020, Arriola-Montenegro et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Arriola-Montenegro, Liliana
Palacios-Revilla, Cecilia D
Cateriano-Alberdi, Maria Paula
Valdivia-Vega, Renzo P
Arriola-Montenegro, Jose
Teenager with a Primary Renal Lymphoma: A Case Report
title Teenager with a Primary Renal Lymphoma: A Case Report
title_full Teenager with a Primary Renal Lymphoma: A Case Report
title_fullStr Teenager with a Primary Renal Lymphoma: A Case Report
title_full_unstemmed Teenager with a Primary Renal Lymphoma: A Case Report
title_short Teenager with a Primary Renal Lymphoma: A Case Report
title_sort teenager with a primary renal lymphoma: a case report
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124830/
https://www.ncbi.nlm.nih.gov/pubmed/32257721
http://dx.doi.org/10.7759/cureus.7181
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