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In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair
The XPD helicase is a central component of the general transcription factor TFIIH which plays major roles in transcription and nucleotide excision repair (NER). Here we present the high-resolution crystal structure of the Arch domain of XPD with its interaction partner MAT1, a central component of t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125077/ https://www.ncbi.nlm.nih.gov/pubmed/32245994 http://dx.doi.org/10.1038/s41467-020-15241-9 |