In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair

The XPD helicase is a central component of the general transcription factor TFIIH which plays major roles in transcription and nucleotide excision repair (NER). Here we present the high-resolution crystal structure of the Arch domain of XPD with its interaction partner MAT1, a central component of t...

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Detalles Bibliográficos
Autores principales: Peissert, Stefan, Sauer, Florian, Grabarczyk, Daniel B., Braun, Cathy, Sander, Gudrun, Poterszman, Arnaud, Egly, Jean-Marc, Kuper, Jochen, Kisker, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125077/
https://www.ncbi.nlm.nih.gov/pubmed/32245994
http://dx.doi.org/10.1038/s41467-020-15241-9

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