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MicroRNA-124 Reduces Arsenic-induced Endoplasmic Reticulum Stress and Neurotoxicity and is Linked with Neurodevelopment in Children

Arsenic (As) exposure adversely affects neurodevelopment in children. Accumulation of misfolded proteins in cells exposed to As leads to endoplasmic reticulum (ER) stress response, which, if not relieved, results in cell death. Despite the potential role of ER stress for As-induced neurotoxicity, th...

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Detalles Bibliográficos
Autores principales: Park, Hae-Ryung, Sun, Ryan, Panganiban, Ronald A., Christiani, David C., Lu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125130/
https://www.ncbi.nlm.nih.gov/pubmed/32246005
http://dx.doi.org/10.1038/s41598-020-62594-8