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Optogenetic restoration of retinal ganglion cell activity in the living primate

Optogenetic therapies for vision restoration aim to confer intrinsic light sensitivity to retinal ganglion cells when photoreceptors have degenerated and light sensitivity has been irreversibly lost. We combine adaptive optics ophthalmoscopy with calcium imaging to optically record optogenetically r...

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Detalles Bibliográficos
Autores principales: McGregor, Juliette E., Godat, Tyler, Dhakal, Kamal R., Parkins, Keith, Strazzeri, Jennifer M., Bateman, Brittany A., Fischer, William S., Williams, David R., Merigan, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125151/
https://www.ncbi.nlm.nih.gov/pubmed/32245977
http://dx.doi.org/10.1038/s41467-020-15317-6