Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes

Proteases have been implicated in the development of many pathological conditions, including cancer. Detection of protease activity in diseased tissues could therefore be useful for diagnosis, prognosis, and the development of novel therapeutic approaches. Due to tight post-translational regulation,...

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Detalles Bibliográficos
Autores principales: Vasiljeva, Olga, Menendez, Elizabeth, Nguyen, Margaret, Craik, Charles S., Michael Kavanaugh, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125177/
https://www.ncbi.nlm.nih.gov/pubmed/32246002
http://dx.doi.org/10.1038/s41598-020-62339-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125177/
https://www.ncbi.nlm.nih.gov/pubmed/32246002
http://dx.doi.org/10.1038/s41598-020-62339-7

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