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In situ structural characterization of early amyloid aggregates in Alzheimer’s disease transgenic mice and Octodon degus
Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer’s disease. In situ identification of early-stage amyloid aggregates in Alzheimer’s disease is relevant for their importance as potential targets for effective drugs. Synchrotron-based...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125182/ https://www.ncbi.nlm.nih.gov/pubmed/32246090 http://dx.doi.org/10.1038/s41598-020-62708-2 |