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In situ structural characterization of early amyloid aggregates in Alzheimer’s disease transgenic mice and Octodon degus

Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer’s disease. In situ identification of early-stage amyloid aggregates in Alzheimer’s disease is relevant for their importance as potential targets for effective drugs. Synchrotron-based...

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Detalles Bibliográficos
Autores principales: Benseny-Cases, Núria, Álvarez-Marimon, Elena, Aso, Ester, Carmona, Margarita, Klementieva, Oxana, Appelhans, Dietmar, Ferrer, Isidre, Cladera, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125182/
https://www.ncbi.nlm.nih.gov/pubmed/32246090
http://dx.doi.org/10.1038/s41598-020-62708-2