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Mechanobiological regulation of placental trophoblast fusion and function through extracellular matrix rigidity

The syncytiotrophoblast is a multinucleated layer that plays a critical role in regulating functions of the human placenta during pregnancy. Maintaining the syncytiotrophoblast layer relies on ongoing fusion of mononuclear cytotrophoblasts throughout pregnancy, and errors in this fusion process are...

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Detalles Bibliográficos
Autores principales: Ma, Zhenwei, Sagrillo-Fagundes, Lucas, Mok, Stephanie, Vaillancourt, Cathy, Moraes, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125233/
https://www.ncbi.nlm.nih.gov/pubmed/32246004
http://dx.doi.org/10.1038/s41598-020-62659-8