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Safety and pharmacokinetics of Withaferin-A in advanced stage high grade osteosarcoma: A phase I trial
BACKGROUND: Withaferin-A (WA), an active principle obtained from a traditional Indian herb known as Ashwagandha or the Indian ginseng, has been shown to prevent and cure urethane-induced lung tumors in mice, and also inhibit the growth of transplanted sarcoma in mice. OBJECTIVES: In this study, we e...
Autores principales: | Pires, Nichelle, Gota, Vikram, Gulia, Ashish, Hingorani, Lal, Agarwal, Manish, Puri, Ajay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125369/ https://www.ncbi.nlm.nih.gov/pubmed/30904387 http://dx.doi.org/10.1016/j.jaim.2018.12.008 |
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