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Safety and pharmacokinetics of Withaferin-A in advanced stage high grade osteosarcoma: A phase I trial

BACKGROUND: Withaferin-A (WA), an active principle obtained from a traditional Indian herb known as Ashwagandha or the Indian ginseng, has been shown to prevent and cure urethane-induced lung tumors in mice, and also inhibit the growth of transplanted sarcoma in mice. OBJECTIVES: In this study, we e...

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Detalles Bibliográficos
Autores principales: Pires, Nichelle, Gota, Vikram, Gulia, Ashish, Hingorani, Lal, Agarwal, Manish, Puri, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125369/
https://www.ncbi.nlm.nih.gov/pubmed/30904387
http://dx.doi.org/10.1016/j.jaim.2018.12.008

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