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A recombinant Fab neutralizes dengue virus in vitro
A recombinant Fab that recognizes a neutralizing epitope located in the (296–400) region of protein E of dengue virus was obtained from cloned hybridoma cells secreting the mouse monoclonal antibody (mAb) 4E11. The Fd and light chain antibody genes were amplified by polymerase chain reaction, cloned...
Autores principales: | Thullier, P, Lafaye, P, Mégret, F, Deubel, V, Jouan, A, Mazié, J.C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science B.V.
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125516/ https://www.ncbi.nlm.nih.gov/pubmed/10361725 http://dx.doi.org/10.1016/S0168-1656(99)00037-1 |
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