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Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents
Human enterovirus (EV) belongs to the picornavirus family, which consists of over 200 medically relevant viruses. A peptidomimetic inhibitor AG7088 was developed to inhibit the 3C protease of rhinovirus (a member of the family), a chymotrypsin-like protease required for viral replication, by forming...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125518/ https://www.ncbi.nlm.nih.gov/pubmed/18583140 http://dx.doi.org/10.1016/j.bmc.2008.06.015 |