Structure and Intracellular Targeting of the SARS-Coronavirus Orf7a Accessory Protein

The open reading frame (ORF) 7a of the SARS-associated coronavirus (SARS-CoV) encodes a unique type I transmembrane protein of unknown function. We have determined the 1.8 Å resolution crystal structure of the N-terminal ectodomain of orf7a, revealing a compact seven-stranded β sandwich unexpectedly...

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Detalles Bibliográficos
Autores principales: Nelson, Christopher A., Pekosz, Andrew, Lee, Chung A., Diamond, Michael S., Fremont, Daved H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125549/
https://www.ncbi.nlm.nih.gov/pubmed/15642263
http://dx.doi.org/10.1016/j.str.2004.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125549/
https://www.ncbi.nlm.nih.gov/pubmed/15642263
http://dx.doi.org/10.1016/j.str.2004.10.010

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