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Structure and Intracellular Targeting of the SARS-Coronavirus Orf7a Accessory Protein

The open reading frame (ORF) 7a of the SARS-associated coronavirus (SARS-CoV) encodes a unique type I transmembrane protein of unknown function. We have determined the 1.8 Å resolution crystal structure of the N-terminal ectodomain of orf7a, revealing a compact seven-stranded β sandwich unexpectedly...

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Detalles Bibliográficos
Autores principales:	Nelson, Christopher A., Pekosz, Andrew, Lee, Chung A., Diamond, Michael S., Fremont, Daved H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125549/ https://www.ncbi.nlm.nih.gov/pubmed/15642263 http://dx.doi.org/10.1016/j.str.2004.10.010

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