Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker

Azidation (TMSN(3), SnCl(4)) of a 9:1 mixture of trans- and cis-5-acetoxy-2-methylisoxazolidin-3-yl-3-phosphonates at the anomeric carbon atom led to the formation of the equimolar mixture of cis- and trans-5-azido-2-methylisoxazolidin-3-yl-3-phosphonates, which were efficiently separated. The 1,3-d...

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Detalles Bibliográficos
Autores principales: Piotrowska, Dorota G., Balzarini, Jan, Głowacka, Iwona E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125624/
https://www.ncbi.nlm.nih.gov/pubmed/22137458
http://dx.doi.org/10.1016/j.ejmech.2011.11.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125624/
https://www.ncbi.nlm.nih.gov/pubmed/22137458
http://dx.doi.org/10.1016/j.ejmech.2011.11.021

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