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Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs

Thiazolides are polypharmacology agents with at least three mechanisms of action against a broad spectrum of parasites, bacteria and viruses. In respiratory viruses they inhibit the replication of orthomyxoviridae and paramyxoviridae at a post-translational level. Nitazoxanide 1a, the prototype thia...

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Detalles Bibliográficos
Autores principales:	Stachulski, Andrew V., Swift, Karl, Cooper, Mark, Reynolds, Stephen, Norton, Daniel, Slonecker, Steven D., Rossignol, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Masson SAS. 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125651/ https://www.ncbi.nlm.nih.gov/pubmed/27750149 http://dx.doi.org/10.1016/j.ejmech.2016.09.080

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