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Identification of DNA methylation regulated novel host genes relevant to inhibition of virus replication in porcine PK15 cell using double stranded RNA mimics and DNA methyltransferase inhibitor

During RNA viruses's replication, double-stranded RNA (dsRNA) is normally produced and induce host innate immune response. Most of gene activation due cytokine mediated but which are due to methylation mediated is still unknown. In the study, DNA methylome was integrated with our previous trans...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoshuo, Ao, Hong, Song, Minyan, Bai, Lijing, He, Weiyong, Wang, Chuduan, Yu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125705/
https://www.ncbi.nlm.nih.gov/pubmed/30315899
http://dx.doi.org/10.1016/j.ygeno.2018.09.020