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Biosynthesis of anti-HCV compounds using thermophilic microorganisms

This work describes the application of thermophilic microorganisms for obtaining 6-halogenated purine nucleosides. Biosynthesis of 6-chloropurine-2′-deoxyriboside and 6-chloropurine riboside was achieved by Geobacillus stearothermophilus CECT 43 with a conversion of 90% and 68%, respectively. Furthe...

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Detalles Bibliográficos
Autores principales:	Rivero, Cintia W., De Benedetti, Eliana C., Sambeth, Jorge E., Lozano, Mario E., Trelles, Jorge A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125738/ https://www.ncbi.nlm.nih.gov/pubmed/22959520 http://dx.doi.org/10.1016/j.bmcl.2012.08.045

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