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Knocking down Disease with siRNAs

Knocking down expression of disease-related genes using small interfering RNAs (siRNAs) has potential for treating a variety of illnesses. This Essay will examine the opportunities for harnessing RNA interference (RNAi) for therapy, as well as the obstacles and possible ways to circumvent them.

Detalles Bibliográficos
Autores principales: Dykxhoorn, Derek M., Lieberman, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125751/
https://www.ncbi.nlm.nih.gov/pubmed/16873051
http://dx.doi.org/10.1016/j.cell.2006.07.007