Binding interaction of quercetin-3-β-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): Structure–activity relationship studies reveal salient pharmacophore features

The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is one of the most promising targets for discovery of drugs against SARS, because of its critical role in the viral life cycle. In this study, a natural compound called quercetin-3-β-galactoside wa...

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Detalles Bibliográficos
Autores principales: Chen, Lili, Li, Jian, Luo, Cheng, Liu, Hong, Xu, Weijun, Chen, Gang, Liew, Oi Wah, Zhu, Weiliang, Puah, Chum Mok, Shen, Xu, Jiang, Hualiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125754/
https://www.ncbi.nlm.nih.gov/pubmed/17046271
http://dx.doi.org/10.1016/j.bmc.2006.09.014

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