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JNK and PI3k/Akt signaling pathways are required for establishing persistent SARS-CoV infection in Vero E6 cells

Persistence was established after most of the SARS-CoV-infected Vero E6 cells died. RNA of the defective interfering virus was not observed in the persistently infected cells by Northern blot analysis. SARS-CoV diluted to 2 PFU failed to establish persistence, suggesting that some particular viruses...

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Detalles Bibliográficos
Autores principales: Mizutani, Tetsuya, Fukushi, Shuetsu, Saijo, Masayuki, Kurane, Ichiro, Morikawa, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125767/
https://www.ncbi.nlm.nih.gov/pubmed/15916886
http://dx.doi.org/10.1016/j.bbadis.2005.04.004