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Apoptosis and loss of virus-specific CD8(+) T-cell memory

CD8(+) T-cell memory to viruses is stable in the absence but volatile in the presence of other infections. Apoptotic events that occur early in acute infections delete pre-existing memory T cells, leaving the host with reduced memory (except for cross-reactive responses) to previously encountered vi...

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Detalles Bibliográficos
Autores principales: Welsh, Raymond M, Bahl, Kapil, Wang, Xiaoting Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125879/
https://www.ncbi.nlm.nih.gov/pubmed/15134774
http://dx.doi.org/10.1016/j.coi.2004.03.020