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Identification of novel ligands for the RNA pseudoknot that regulate −1 ribosomal frameshifting
In many viruses, −1 ribosomal frameshifting (−1RF) regulates synthesis of proteins and is crucial for virus production. An RNA pseudoknot is one of the essential components of the viral −1RF system. Thermodynamic or kinetic control of pseudoknot folding may be important in regulating the efficiency...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125880/ https://www.ncbi.nlm.nih.gov/pubmed/18321712 http://dx.doi.org/10.1016/j.bmc.2008.02.025 |