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Determinants of translational fidelity and efficiency in vertebrate mRNAs

This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5′-non-coding region on the efficiency of translation of messenger RNA molecules.

Detalles Bibliográficos
Autor principal: Kozak, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125885/
https://www.ncbi.nlm.nih.gov/pubmed/7880897
http://dx.doi.org/10.1016/0300-9084(94)90182-1
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author Kozak, M.
author_facet Kozak, M.
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description This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5′-non-coding region on the efficiency of translation of messenger RNA molecules.
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spelling pubmed-71258852020-04-08 Determinants of translational fidelity and efficiency in vertebrate mRNAs Kozak, M. Biochimie Article This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5′-non-coding region on the efficiency of translation of messenger RNA molecules. Published by Elsevier Masson SAS 1994 2003-01-27 /pmc/articles/PMC7125885/ /pubmed/7880897 http://dx.doi.org/10.1016/0300-9084(94)90182-1 Text en Copyright © 1994 Published by Elsevier Masson SAS. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kozak, M.
Determinants of translational fidelity and efficiency in vertebrate mRNAs
title Determinants of translational fidelity and efficiency in vertebrate mRNAs
title_full Determinants of translational fidelity and efficiency in vertebrate mRNAs
title_fullStr Determinants of translational fidelity and efficiency in vertebrate mRNAs
title_full_unstemmed Determinants of translational fidelity and efficiency in vertebrate mRNAs
title_short Determinants of translational fidelity and efficiency in vertebrate mRNAs
title_sort determinants of translational fidelity and efficiency in vertebrate mrnas
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125885/
https://www.ncbi.nlm.nih.gov/pubmed/7880897
http://dx.doi.org/10.1016/0300-9084(94)90182-1
work_keys_str_mv AT kozakm determinantsoftranslationalfidelityandefficiencyinvertebratemrnas