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Determinants of translational fidelity and efficiency in vertebrate mRNAs
This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5′-non-coding region on the efficiency of translation of messenger RNA molecules.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Published by Elsevier Masson SAS
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125885/ https://www.ncbi.nlm.nih.gov/pubmed/7880897 http://dx.doi.org/10.1016/0300-9084(94)90182-1 |
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author | Kozak, M. |
author_facet | Kozak, M. |
author_sort | Kozak, M. |
collection | PubMed |
description | This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5′-non-coding region on the efficiency of translation of messenger RNA molecules. |
format | Online Article Text |
id | pubmed-7125885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1994 |
publisher | Published by Elsevier Masson SAS |
record_format | MEDLINE/PubMed |
spelling | pubmed-71258852020-04-08 Determinants of translational fidelity and efficiency in vertebrate mRNAs Kozak, M. Biochimie Article This article reviews current knowledge on the mechanisms affecting the fidelity of initiation codon selection, and discusses the effects of structural features in the 5′-non-coding region on the efficiency of translation of messenger RNA molecules. Published by Elsevier Masson SAS 1994 2003-01-27 /pmc/articles/PMC7125885/ /pubmed/7880897 http://dx.doi.org/10.1016/0300-9084(94)90182-1 Text en Copyright © 1994 Published by Elsevier Masson SAS. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Kozak, M. Determinants of translational fidelity and efficiency in vertebrate mRNAs |
title | Determinants of translational fidelity and efficiency in vertebrate mRNAs |
title_full | Determinants of translational fidelity and efficiency in vertebrate mRNAs |
title_fullStr | Determinants of translational fidelity and efficiency in vertebrate mRNAs |
title_full_unstemmed | Determinants of translational fidelity and efficiency in vertebrate mRNAs |
title_short | Determinants of translational fidelity and efficiency in vertebrate mRNAs |
title_sort | determinants of translational fidelity and efficiency in vertebrate mrnas |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125885/ https://www.ncbi.nlm.nih.gov/pubmed/7880897 http://dx.doi.org/10.1016/0300-9084(94)90182-1 |
work_keys_str_mv | AT kozakm determinantsoftranslationalfidelityandefficiencyinvertebratemrnas |