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PCK1 Regulates Glycolysis and Tumor Progression in Clear Cell Renal Cell Carcinoma Through LDHA

BACKGROUND: Suppressed gluconeogenesis and increased glycolysis are common in clear cell renal cell carcinoma (ccRCC). Phosphoenolpyruvate carboxykinase 1 (PCK1) is a rate-limiting gluconeogenesis enzyme. However, the role of PCK1 in tumor metabolism and progression remains unclear. METHODS: Artific...

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Detalles Bibliográficos
Autores principales:	Shi, Liang, An, Shuxian, Liu, Ying, Liu, Jianjun, Wang, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125947/ https://www.ncbi.nlm.nih.gov/pubmed/32280238 http://dx.doi.org/10.2147/OTT.S241717

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