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Intranasal immunisation with recombinant adenovirus vaccines protects against a lethal challenge with pneumonia virus of mice

Pneumonia virus of mice (PVM) infection of BALB/c mice induces bronchiolitis leading to a fatal pneumonia in a dose-dependent manner, closely paralleling the development of severe disease during human respiratory syncytial virus infection in man, and is thus a recognised model in which to study the...

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Detalles Bibliográficos
Autores principales: Maunder, Helen E., Taylor, Geraldine, Leppard, Keith N., Easton, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125973/
https://www.ncbi.nlm.nih.gov/pubmed/26529077
http://dx.doi.org/10.1016/j.vaccine.2015.10.105