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Pushing the limits of the scanning mechanism for initiation of translation

Selection of the translational initiation site in most eukaryotic mRNAs appears to occur via a scanning mechanism which predicts that proximity to the 5′ end plays a dominant role in identifying the start codon. This ‘position effect’ is seen in cases where a mutation creates an AUG codon upstream f...

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Detalles Bibliográficos
Autor principal: Kozak, Marilyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126118/
https://www.ncbi.nlm.nih.gov/pubmed/12459250
http://dx.doi.org/10.1016/S0378-1119(02)01056-9