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Pushing the limits of the scanning mechanism for initiation of translation
Selection of the translational initiation site in most eukaryotic mRNAs appears to occur via a scanning mechanism which predicts that proximity to the 5′ end plays a dominant role in identifying the start codon. This ‘position effect’ is seen in cases where a mutation creates an AUG codon upstream f...
Autor principal: | Kozak, Marilyn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126118/ https://www.ncbi.nlm.nih.gov/pubmed/12459250 http://dx.doi.org/10.1016/S0378-1119(02)01056-9 |
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