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CFD simulation of airborne pathogen transport due to human activities

Computational Fluid Dynamics (CFD) is an increasingly popular tool for studying the impact of design interventions on the transport of infectious microorganisms. While much of the focus is on respiratory infections, there is substantial evidence that certain pathogens, such as those which colonise t...

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Detalles Bibliográficos
Autores principales: Hathway, E.A., Noakes, C.J., Sleigh, P.A., Fletcher, L.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126191/
https://www.ncbi.nlm.nih.gov/pubmed/32288014
http://dx.doi.org/10.1016/j.buildenv.2011.06.001
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author Hathway, E.A.
Noakes, C.J.
Sleigh, P.A.
Fletcher, L.A.
author_facet Hathway, E.A.
Noakes, C.J.
Sleigh, P.A.
Fletcher, L.A.
author_sort Hathway, E.A.
collection PubMed
description Computational Fluid Dynamics (CFD) is an increasingly popular tool for studying the impact of design interventions on the transport of infectious microorganisms. While much of the focus is on respiratory infections, there is substantial evidence that certain pathogens, such as those which colonise the skin, can be released into, and transported through the air through routine activities. In these situations the bacteria is released over a volume of space, with different intensities and locations varying in time rather than being released at a single point. This paper considers the application of CFD modelling to the evaluation of risk from this type of bioaerosol generation. An experimental validation study provides a direct comparison between CFD simulations and bioaerosol distribution, showing that passive scalar and particle tracking approaches are both appropriate for small particle bioaerosols. The study introduces a zonal source, which aims to represent the time averaged release of bacteria from an activity within a zone around the entire location the release takes place. This approach is shown to perform well when validated numerically though comparison with the time averaged dispersion patterns from a transient source. However, the ability of a point source to represent such dispersion is dependent on airflow regime. The applicability of the model is demonstrated using a simulation of an isolation room representing the release of bacteria from bedmaking.
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spelling pubmed-71261912020-04-08 CFD simulation of airborne pathogen transport due to human activities Hathway, E.A. Noakes, C.J. Sleigh, P.A. Fletcher, L.A. Build Environ Article Computational Fluid Dynamics (CFD) is an increasingly popular tool for studying the impact of design interventions on the transport of infectious microorganisms. While much of the focus is on respiratory infections, there is substantial evidence that certain pathogens, such as those which colonise the skin, can be released into, and transported through the air through routine activities. In these situations the bacteria is released over a volume of space, with different intensities and locations varying in time rather than being released at a single point. This paper considers the application of CFD modelling to the evaluation of risk from this type of bioaerosol generation. An experimental validation study provides a direct comparison between CFD simulations and bioaerosol distribution, showing that passive scalar and particle tracking approaches are both appropriate for small particle bioaerosols. The study introduces a zonal source, which aims to represent the time averaged release of bacteria from an activity within a zone around the entire location the release takes place. This approach is shown to perform well when validated numerically though comparison with the time averaged dispersion patterns from a transient source. However, the ability of a point source to represent such dispersion is dependent on airflow regime. The applicability of the model is demonstrated using a simulation of an isolation room representing the release of bacteria from bedmaking. Elsevier Ltd. 2011-12 2011-06-17 /pmc/articles/PMC7126191/ /pubmed/32288014 http://dx.doi.org/10.1016/j.buildenv.2011.06.001 Text en Copyright © 2011 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Hathway, E.A.
Noakes, C.J.
Sleigh, P.A.
Fletcher, L.A.
CFD simulation of airborne pathogen transport due to human activities
title CFD simulation of airborne pathogen transport due to human activities
title_full CFD simulation of airborne pathogen transport due to human activities
title_fullStr CFD simulation of airborne pathogen transport due to human activities
title_full_unstemmed CFD simulation of airborne pathogen transport due to human activities
title_short CFD simulation of airborne pathogen transport due to human activities
title_sort cfd simulation of airborne pathogen transport due to human activities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126191/
https://www.ncbi.nlm.nih.gov/pubmed/32288014
http://dx.doi.org/10.1016/j.buildenv.2011.06.001
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