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A novel method for making human monoclonal antibodies

We have developed a B cell immortalization method for low B cell numbers per well using simultaneous B cell stimulation by CpG2006 and B cell infection by Epstein-Barr virus (EBV), followed by an additional CpG2006 and interleukin-2 (IL-2) stimulus. Using this method, immunoglobulin G (IgG)-producin...

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Detalles Bibliográficos
Autores principales:	Fraussen, J., Vrolix, K., Martinez-Martinez, P., Losen, M., Meulemans, E., De Baets, M.H., Stinissen, P., Somers, V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126289/ https://www.ncbi.nlm.nih.gov/pubmed/20732843 http://dx.doi.org/10.1016/j.jaut.2010.05.001

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