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Antileishmanial activity of MDL 28170, a potent calpain inhibitor

Several calpain inhibitors are under development and some are useful agents against important human pathogens. We therefore investigated the effect of MDL 28170, a potent calpain inhibitor, on the growth of Leishmania amazonensis. After 48 h of treatment, the inhibitor exhibited a dose-dependent ant...

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Detalles Bibliográficos
Autores principales:	d’Avila-Levy, Claudia M., Marinho, Fernanda A., Santos, Lívia O., Martins, Juliana L., Santos, André L.S., Branquinha, Marta H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. and the International Society of Chemotherapy. 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126437/ https://www.ncbi.nlm.nih.gov/pubmed/16842979 http://dx.doi.org/10.1016/j.ijantimicag.2006.03.021

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