Controlled release of PEI/DNA complexes from mannose-bearing chitosan microspheres as a potent delivery system to enhance immune response to HBV DNA vaccine

A novel approach involving the preparation of mannose-bearing chitosan microspheres with entrapping complexes of HBV DNA and PEI was developed to improve the delivery of DNA into antigen-presenting cells (APCs) after intramuscular (i.m.) injection. Compared with the traditional chitosan microspheres...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xianfeng, Liu, Bin, Yu, Xianghui, Zha, Xiao, Zhang, Xizhen, Chen, Yu, Wang, Xueyun, Jin, Yinghua, Wu, Yongge, Chen, Yue, Shan, Yaming, Chen, Yan, Liu, Junqiu, Kong, Wei, Shen, Jiacong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126484/
https://www.ncbi.nlm.nih.gov/pubmed/17630014
http://dx.doi.org/10.1016/j.jconrel.2007.05.018

Ejemplares similares

Ejemplares similares