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Antifungal anthraquinones from Saprosma fragrans

A new 3,4-dihydroxy-1-methoxy anthraquinone-2-corboxaldehyde (1) together with a known anthraquinone, damnacanthal (2), were isolated from the chloroform fraction of the aerial part (whole plant without root) of Saprosma fragrans. The isolated anthraquinones (1) and (2) were found to exhibit antifun...

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Autores principales: Singh, D.N., Verma, N., Raghuwanshi, S., Shukla, P.K., Kulshreshtha, D.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126606/
https://www.ncbi.nlm.nih.gov/pubmed/16824761
http://dx.doi.org/10.1016/j.bmcl.2006.06.027
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author Singh, D.N.
Verma, N.
Raghuwanshi, S.
Shukla, P.K.
Kulshreshtha, D.K.
author_facet Singh, D.N.
Verma, N.
Raghuwanshi, S.
Shukla, P.K.
Kulshreshtha, D.K.
author_sort Singh, D.N.
collection PubMed
description A new 3,4-dihydroxy-1-methoxy anthraquinone-2-corboxaldehyde (1) together with a known anthraquinone, damnacanthal (2), were isolated from the chloroform fraction of the aerial part (whole plant without root) of Saprosma fragrans. The isolated anthraquinones (1) and (2) were found to exhibit antifungal activity against Trichophyton mentagrophytes and Sporitrichum schenckii. Their structures were established by chemical and spectral analysis.
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spelling pubmed-71266062020-04-08 Antifungal anthraquinones from Saprosma fragrans Singh, D.N. Verma, N. Raghuwanshi, S. Shukla, P.K. Kulshreshtha, D.K. Bioorg Med Chem Lett Article A new 3,4-dihydroxy-1-methoxy anthraquinone-2-corboxaldehyde (1) together with a known anthraquinone, damnacanthal (2), were isolated from the chloroform fraction of the aerial part (whole plant without root) of Saprosma fragrans. The isolated anthraquinones (1) and (2) were found to exhibit antifungal activity against Trichophyton mentagrophytes and Sporitrichum schenckii. Their structures were established by chemical and spectral analysis. Elsevier Ltd. 2006-09-01 2006-07-07 /pmc/articles/PMC7126606/ /pubmed/16824761 http://dx.doi.org/10.1016/j.bmcl.2006.06.027 Text en Copyright © 2006 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Singh, D.N.
Verma, N.
Raghuwanshi, S.
Shukla, P.K.
Kulshreshtha, D.K.
Antifungal anthraquinones from Saprosma fragrans
title Antifungal anthraquinones from Saprosma fragrans
title_full Antifungal anthraquinones from Saprosma fragrans
title_fullStr Antifungal anthraquinones from Saprosma fragrans
title_full_unstemmed Antifungal anthraquinones from Saprosma fragrans
title_short Antifungal anthraquinones from Saprosma fragrans
title_sort antifungal anthraquinones from saprosma fragrans
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126606/
https://www.ncbi.nlm.nih.gov/pubmed/16824761
http://dx.doi.org/10.1016/j.bmcl.2006.06.027
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