De novo RNA synthesis and homology modeling of the classical swine fever virus RNA polymerase

Classical swine fever virus (CSFV) non-structural protein 5B (NS5B) encodes an RNA-dependent RNA polymerase (RdRp), a key enzyme which initiates RNA replication by a de novo mechanism without a primer and is a potential target for anti-virus therapy. We expressed the NS5B protein in Escherichia coli...

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Detalles Bibliográficos
Autores principales: Zhang, Pengwei, Xie, Jian, Yi, Guanghui, Zhang, Chuyu, Zhou, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126667/
https://www.ncbi.nlm.nih.gov/pubmed/16022897
http://dx.doi.org/10.1016/j.virusres.2005.03.003

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