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One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation
Cyclophilin A (CypA) is a ubiquitous cellular enzyme playing critical roles in many biological processes, and its inhibitor has been reported to have potential immunosuppressive activity. In this work, we reported a novel quinoxaline derivative, 2,3-di(furan-2-yl)-6-(3-N,N-diethylcarbamoyl-piperidin...
Autores principales: | Li, Jian, Chen, Jing, Zhang, Li, Wang, Feng, Gui, Chunshan, Qin, Yu, Xu, Qiang, Liu, Hong, Nan, Fajun, Shen, Jingkang, Bai, Donglu, Chen, Kaixian, Shen, Xu, Jiang, Hualiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126670/ https://www.ncbi.nlm.nih.gov/pubmed/16682211 http://dx.doi.org/10.1016/j.bmc.2006.04.026 |
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