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Clinical study of transcutaneous vaccination using a hydrogel patch for tetanus and diphtheria
Transcutaneous immunization (TCI) is a non-invasive and easy-to-use vaccination method. We demonstrated the efficacy and safety of a transcutaneous vaccine formulation using a hydrogel patch in animal experiments. In the present study, we performed a clinical study to apply our TCI formulation for v...
Autores principales: | Hirobe, Sachiko, Matsuo, Kazuhiko, Quan, Ying-Shu, Kamiyama, Fumio, Morito, Hironori, Asada, Hideo, Takaya, Yusuke, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126733/ https://www.ncbi.nlm.nih.gov/pubmed/22230592 http://dx.doi.org/10.1016/j.vaccine.2011.12.130 |
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