Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa

SARS-CoV papain-like protease (PLpro) is an important antiviral target due to its key roles in SARS virus replication. The MeOH extracts of the fruits of the Paulownia tree yielded many small molecules capable of targeting PLpro. Five of these compounds were new geranylated flavonoids, tomentin A, t...

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Detalles Bibliográficos
Autores principales: Cho, Jung Keun, Curtis-Long, Marcus J., Lee, Kon Ho, Kim, Dae Wook, Ryu, Hyung Won, Yuk, Heung Joo, Park, Ki Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. Published by Elsevier Ltd. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126831/
https://www.ncbi.nlm.nih.gov/pubmed/23623680
http://dx.doi.org/10.1016/j.bmc.2013.03.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126831/
https://www.ncbi.nlm.nih.gov/pubmed/23623680
http://dx.doi.org/10.1016/j.bmc.2013.03.027

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