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Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa
SARS-CoV papain-like protease (PLpro) is an important antiviral target due to its key roles in SARS virus replication. The MeOH extracts of the fruits of the Paulownia tree yielded many small molecules capable of targeting PLpro. Five of these compounds were new geranylated flavonoids, tomentin A, t...
Autores principales: | Cho, Jung Keun, Curtis-Long, Marcus J., Lee, Kon Ho, Kim, Dae Wook, Ryu, Hyung Won, Yuk, Heung Joo, Park, Ki Hun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd. Published by Elsevier Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126831/ https://www.ncbi.nlm.nih.gov/pubmed/23623680 http://dx.doi.org/10.1016/j.bmc.2013.03.027 |
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