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Intragastric administration of attenuated Salmonella typhimurium harbouring transmissible gastroenteritis virus (TGEV) DNA vaccine induced specific antibody production

Attenuated Salmonella typhimurium was selected as a transgenic vehicle for the development of live mucosal vaccines against transmissible gastroenteritis virus (TGEV). A 2.2 kb DNA fragment, encoding for N-terminal domain glycoprotein S of TGEV, was amplified by RT-PCR and cloned into eukaryotic exp...

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Detalles Bibliográficos
Autores principales: Yang, Heng, Cao, Sanjie, Huang, Xiaobo, Liu, Jiawen, Tang, Ying, Wen, Xintian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126841/
https://www.ncbi.nlm.nih.gov/pubmed/19573642
http://dx.doi.org/10.1016/j.vaccine.2009.06.050