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Immunoendocrine dysbalance during uncontrolled T. cruzi infection is associated with the acquisition of a Th-1-like phenotype by Foxp3(+) T cells
We previously showed that Trypanosomacruzi infection in C57BL/6 mice results in a lethal infection linked to unbalanced pro- and anti-inflammatory mediators production. Here, we examined the dynamics of CD4(+)Foxp3(+) regulatory T (Treg) cells within this inflammatory and highly Th1-polarized enviro...
Autores principales: | González, Florencia B., Villar, Silvina R., Fernández Bussy, Rodrigo, Martin, Gaëlle H., Pérol, Louis, Manarin, Romina, Spinelli, Silvana V., Pilon, Caroline, Cohen, José Laurent, Bottasso, Oscar A., Piaggio, Eliane, Pérez, Ana R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126853/ https://www.ncbi.nlm.nih.gov/pubmed/25483139 http://dx.doi.org/10.1016/j.bbi.2014.11.016 |
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