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Dideoxy fluoro-ketopyranosyl nucleosides as potent antiviral agents: Synthesis and biological evaluation of 2,3- and 3,4-dideoxy-3-fluoro-4- and -2-keto-β-d-glucopyranosyl derivatives of N(4)-benzoyl cytosine
The synthesis of the dideoxy fluoro ketopyranonucleoside analogues, 1-(2,3-dideoxy-3-fluoro-6-O-trityl-β-d-glycero-hexopyranosyl-4-ulose)-N(4)-benzoyl cytosine (7a), 1-(3,4-dideoxy-3-fluoro-6-O-trityl-β-d-glycero-hexopyranosyl-2-ulose)-N(4)-benzoyl cytosine (13a) and their detritylated analogues 8a...
Autores principales: | Manta, Stella, Tsoukala, Evangelia, Tzioumaki, Niki, Goropevšek, Aleš, Pamulapati, Ravi Teja, Cencič, Avrelija, Balzarini, Jan, Komiotis, Dimitri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Masson SAS.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126854/ https://www.ncbi.nlm.nih.gov/pubmed/19246130 http://dx.doi.org/10.1016/j.ejmech.2009.01.020 |
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