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Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava

Phlorotannins have been isolated and are the first of their type showing competitively inhibitory activity toward SARS-CoV 3CLpro. Dieckol showed the most potent SARS-CoV 3CLpro trans/cis-cleavage inhibitory effects with high association rate. [Figure: see text]

Detalles Bibliográficos
Autores principales:	Park, Ji-Young, Kim, Jang Hoon, Kwon, Jung Min, Kwon, Hyung-Jun, Jeong, Hyung Jae, Kim, Young Min, Kim, Doman, Lee, Woo Song, Ryu, Young Bae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126891/ https://www.ncbi.nlm.nih.gov/pubmed/23647823 http://dx.doi.org/10.1016/j.bmc.2013.04.026

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