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Enhanced immune responses to viral epitopes by combining macrophage-inducible expression with multimeric display on a Salmonella vector
In this study, the immunogenicity of chimeric 987P fimbriae on a Salmonella vaccine strain was improved by optimizing fimbrial expression. The constitutive tetA promoter and the in vivo activated nirB and pagC promoters were evaluated for their use to express two epitopes of the transmissible gastro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd.
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126928/ https://www.ncbi.nlm.nih.gov/pubmed/11282213 http://dx.doi.org/10.1016/S0264-410X(00)00541-7 |