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T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections
A series of pyrazinecarboxamide derivatives T-705 (favipiravir), T-1105 and T-1106 were discovered to be candidate antiviral drugs. These compounds have demonstrated good activity in treating viral infections in laboratory animals caused by various RNA viruses, including influenza virus, arenaviruse...
Autores principales: | Furuta, Yousuke, Takahashi, Kazumi, Shiraki, Kimiyasu, Sakamoto, Kenichi, Smee, Donald F., Barnard, Dale L., Gowen, Brian B., Julander, Justin G., Morrey, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127082/ https://www.ncbi.nlm.nih.gov/pubmed/19428599 http://dx.doi.org/10.1016/j.antiviral.2009.02.198 |
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