Cargando…

Murine coronaviruses: the histopathology of disease induced by intranasal inoculation

Mice inoculated intranasally with murine coronaviruses (mouse hepatitus viruses) were killed daily for seven days. Lung and liver sections stained by the immunopcroxidasc technique indicated that with three of the four strains examined viral localisation and replication in the lung preceded that fou...

Descripción completa

Detalles Bibliográficos
Autores principales: Carthew, P., Sparrow, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1981
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127176/
https://www.ncbi.nlm.nih.gov/pubmed/6265998
http://dx.doi.org/10.1016/S0034-5288(18)32540-2
_version_ 1783516303963717632
author Carthew, P.
Sparrow, S.
author_facet Carthew, P.
Sparrow, S.
author_sort Carthew, P.
collection PubMed
description Mice inoculated intranasally with murine coronaviruses (mouse hepatitus viruses) were killed daily for seven days. Lung and liver sections stained by the immunopcroxidasc technique indicated that with three of the four strains examined viral localisation and replication in the lung preceded that found in (he liver. Thus, infection by the respiratory route may be of importance in the Iransmission of these viruses.
format Online
Article
Text
id pubmed-7127176
institution National Center for Biotechnology Information
language English
publishDate 1981
publisher Published by Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-71271762020-04-08 Murine coronaviruses: the histopathology of disease induced by intranasal inoculation Carthew, P. Sparrow, S. Res Vet Sci Article Mice inoculated intranasally with murine coronaviruses (mouse hepatitus viruses) were killed daily for seven days. Lung and liver sections stained by the immunopcroxidasc technique indicated that with three of the four strains examined viral localisation and replication in the lung preceded that found in (he liver. Thus, infection by the respiratory route may be of importance in the Iransmission of these viruses. Published by Elsevier Ltd. 1981-05 2018-11-13 /pmc/articles/PMC7127176/ /pubmed/6265998 http://dx.doi.org/10.1016/S0034-5288(18)32540-2 Text en Copyright © 1981 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Carthew, P.
Sparrow, S.
Murine coronaviruses: the histopathology of disease induced by intranasal inoculation
title Murine coronaviruses: the histopathology of disease induced by intranasal inoculation
title_full Murine coronaviruses: the histopathology of disease induced by intranasal inoculation
title_fullStr Murine coronaviruses: the histopathology of disease induced by intranasal inoculation
title_full_unstemmed Murine coronaviruses: the histopathology of disease induced by intranasal inoculation
title_short Murine coronaviruses: the histopathology of disease induced by intranasal inoculation
title_sort murine coronaviruses: the histopathology of disease induced by intranasal inoculation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127176/
https://www.ncbi.nlm.nih.gov/pubmed/6265998
http://dx.doi.org/10.1016/S0034-5288(18)32540-2
work_keys_str_mv AT carthewp murinecoronavirusesthehistopathologyofdiseaseinducedbyintranasalinoculation
AT sparrows murinecoronavirusesthehistopathologyofdiseaseinducedbyintranasalinoculation