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Pathogenic role of HMGB1 in SARS?

High mobility group box 1 protein (HMGB1) is released by necrotic cells or activated macrophages/monocytes, and functions as a late mediator of lethal systemic and local pulmonary inflammation. Passive immunization with anti-HMGB1 antibodies confers significant protection against lethal endotoxemia,...

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Detalles Bibliográficos
Autores principales: Chen, Guoqian, Chen, Da-zhi, Li, Jianhua, Czura, Christopher J., Tracey, Kevin J., Sama, Andrew E., Wang, Haichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127179/
https://www.ncbi.nlm.nih.gov/pubmed/15325019
http://dx.doi.org/10.1016/j.mehy.2004.01.037