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A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks

Efficient vaccination strategy is crucial for controlling recurrent epidemic spreading on networks. In this paper, based on the analysis of real epidemic data and simulations, it’s found that the risk indicator of recurrent epidemic outbreaks could be determined by the ratio of the epidemic infectio...

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Detalles Bibliográficos
Autores principales: Chen, Dandan, Zheng, Muhua, Zhao, Ming, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127246/
https://www.ncbi.nlm.nih.gov/pubmed/32288354
http://dx.doi.org/10.1016/j.chaos.2018.04.026
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author Chen, Dandan
Zheng, Muhua
Zhao, Ming
Zhang, Yu
author_facet Chen, Dandan
Zheng, Muhua
Zhao, Ming
Zhang, Yu
author_sort Chen, Dandan
collection PubMed
description Efficient vaccination strategy is crucial for controlling recurrent epidemic spreading on networks. In this paper, based on the analysis of real epidemic data and simulations, it’s found that the risk indicator of recurrent epidemic outbreaks could be determined by the ratio of the epidemic infection rate of the year to the average infected density of the former year. According to the risk indicator, the dynamic vaccination probability of each year can be designed to suppress the epidemic outbreaks. Our simulation results show that the dynamic vaccination strategy could effectively decrease the maximal and average infected density, and meanwhile increase the time intervals of epidemic outbreaks and individuals attacked by epidemic. In addition, our results indicate that to depress the influenza outbreaks, it is not necessary to keep the vaccination probability high every year; and adjusting the vaccination probability at right time could decrease the outbreak risks with lower costs. Our findings may present a theoretical guidance for the government and the public to control the recurrent epidemic outbreaks.
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spelling pubmed-71272462020-04-08 A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks Chen, Dandan Zheng, Muhua Zhao, Ming Zhang, Yu Chaos Solitons Fractals Article Efficient vaccination strategy is crucial for controlling recurrent epidemic spreading on networks. In this paper, based on the analysis of real epidemic data and simulations, it’s found that the risk indicator of recurrent epidemic outbreaks could be determined by the ratio of the epidemic infection rate of the year to the average infected density of the former year. According to the risk indicator, the dynamic vaccination probability of each year can be designed to suppress the epidemic outbreaks. Our simulation results show that the dynamic vaccination strategy could effectively decrease the maximal and average infected density, and meanwhile increase the time intervals of epidemic outbreaks and individuals attacked by epidemic. In addition, our results indicate that to depress the influenza outbreaks, it is not necessary to keep the vaccination probability high every year; and adjusting the vaccination probability at right time could decrease the outbreak risks with lower costs. Our findings may present a theoretical guidance for the government and the public to control the recurrent epidemic outbreaks. Elsevier Ltd. 2018-08 2018-06-04 /pmc/articles/PMC7127246/ /pubmed/32288354 http://dx.doi.org/10.1016/j.chaos.2018.04.026 Text en © 2018 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Chen, Dandan
Zheng, Muhua
Zhao, Ming
Zhang, Yu
A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks
title A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks
title_full A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks
title_fullStr A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks
title_full_unstemmed A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks
title_short A dynamic vaccination strategy to suppress the recurrent epidemic outbreaks
title_sort dynamic vaccination strategy to suppress the recurrent epidemic outbreaks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127246/
https://www.ncbi.nlm.nih.gov/pubmed/32288354
http://dx.doi.org/10.1016/j.chaos.2018.04.026
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