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Flaviviral methyltransferase/RNA interaction: Structural basis for enzyme inhibition
Flaviviruses are the causative agents of severe diseases such as Dengue or Yellow fever. The replicative machinery used by the virus is based on few enzymes including a methyltransferase, located in the N-terminal domain of the NS5 protein. Flaviviral methyltransferases are involved in the last two...
Autores principales: | Milani, Mario, Mastrangelo, Eloise, Bollati, Michela, Selisko, Barbara, Decroly, Etienne, Bouvet, Mickaël, Canard, Bruno, Bolognesi, Martino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127253/ https://www.ncbi.nlm.nih.gov/pubmed/19501254 http://dx.doi.org/10.1016/j.antiviral.2009.03.001 |
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