Human metapneumovirus infection in an immunocompetent adult presenting as mononucleosis-like illness

A 37-year-old man was presented with incidental findings of neutropenia, atypical lymphocytosis, thrombocytopenia and deranged liver parenchymal enzymes. Four days later, he developed fever, sore throat and cervical lymphadenopathy, compatible with mononucleosis-like illness (MLI). Polymerase chain...

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Detalles Bibliográficos
Autores principales: Li, Iris W.S., To, Kelvin K.W., Tang, Bone S.F., Chan, Kwok-Hung, Hui, Chee-Kin, Cheng, Vincent C.C., Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Society. Published by Elsevier Ltd. 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127351/
https://www.ncbi.nlm.nih.gov/pubmed/18423876
http://dx.doi.org/10.1016/j.jinf.2008.03.005
Descripción
Sumario:A 37-year-old man was presented with incidental findings of neutropenia, atypical lymphocytosis, thrombocytopenia and deranged liver parenchymal enzymes. Four days later, he developed fever, sore throat and cervical lymphadenopathy, compatible with mononucleosis-like illness (MLI). Polymerase chain reaction (PCR) and viral culture of the nasopharyngeal swab showed human metapneumovirus (hMPV). There was a ≥4-fold rise in IgG against hMPV. This is the first case report illustrating the natural clinical course of hMPV-related MLI.

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