Cargando…
Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13
Severe acute respiratory syndrome (SARS) is an infectious disease with a strong potential for transmission upon close personal contact and is caused by the SARS-coronavirus (CoV). However, there are no natural or synthetic compounds currently available that can inhibit SARS-CoV. We examined the inhi...
Autores principales: | Yu, Mi-Sun, Lee, June, Lee, Jin Moo, Kim, Younggyu, Chin, Young-Won, Jee, Jun-Goo, Keum, Young-Sam, Jeong, Yong-Joo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127438/ https://www.ncbi.nlm.nih.gov/pubmed/22578462 http://dx.doi.org/10.1016/j.bmcl.2012.04.081 |
Ejemplares similares
-
Cooperative translocation enhances the unwinding of duplex DNA by SARS coronavirus helicase nsP13
por: Lee, Na-Ra, et al.
Publicado: (2010) -
A high ATP concentration enhances the cooperative translocation of the SARS coronavirus helicase nsP13 in the unwinding of duplex RNA
por: Jang, Kyoung-Jin, et al.
Publicado: (2020) -
Cooperative Activity of SARS Coronavirus Nsp13 Helicase Characterized by Single Molecule FRET
por: Im, Hyeryeon, et al.
Publicado: (2015) -
A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance
por: Grimes, Samantha L., et al.
Publicado: (2023) -
Development of chemical inhibitors of the SARS coronavirus: Viral helicase as a potential target
por: Keum, Young-Sam, et al.
Publicado: (2012)